Wayfinding, Spatial Learning, and Other Sickness Responses Following Acute Activation of the Immune System in Aging

Project Description

The purpose of this project is to examine the impact of an acute immune challenge on cognition and other responses in aging.  The aim is to characterize acute infections in the elderly which could provide the foundation for early recognition of behavioral changes or biomarkers, leading to the identification and testing of appropriate interventions.  The primary focus is the development and/or conduct of a study designed to characterize wayfinding and other responses in elderly people experiencing an infection or an acute immune challenge.  Another focus will be the analysis of previously collected data on spatial learning and other sickness responses in aged rats following administration of intraperitoneal Lipopolysaccharide (LPS). This data will be utilized in the development of a research and/or grant proposal. A third focus is the development of a study using publicly available database to study the effects of infection on cognition.

Work Schedule

Unless there is an ongoing study schedule/protocol, days/times are negotiable.

Additional Notes

  • Ongoing work with IRB submission as needed
  • Conduct data collection with study of the elderly at local Flint sites
  • Ongoing troubleshooting issues arising from conduct of study
  • Conduct review of literature
  • Data entry and analysis
  • Assist with abstract submission
  • Assist with grant application
  • Assist with manuscript preparation
  • Assist with poster preparation
  • Assist with other research related activities
  • Develop study using publicly available database
  • Assist with project design
  • Data collection – may involve working with animal protocol

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Job ID: 172038
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Job Detail
Job Opening ID
Nursing (School of)
Fall 2019 Only
Work could be done by someone not coming to campus (e.g., online or non-local student)
What majors can apply?
  • ANY Graduate Student
Faculty Sponsor
Faculty Name
Barbara Kupferschmid
Nursing (School of)
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